LECO Solutions for Mass Spectrometry

Comprehensive two-dimensional gas chromatography with flame ionization detection (GCxGC-FID) has proven to be one of the most effective analytical methods for analyzing complex mixtures, allowing for the detailed separation and identification of the hydrocarbons present while providing efficient, high-resolution chromatographic separations.

This application note describes how to use a simple workflow with the LECO Paradigm system to fulfill the requirements of the ASTM D8396 test method to quantitatively determine mass % of total n-paraffins, iso-paraffins, naphthenes, 1-ring aromatics, and 2-ring aromatics using reverse-fill flush flow modulated comprehensive two-dimensional gas chromatography–flame ionization detection (GCxGC-FID). Understanding of bulk composition is crucial for fast-track certification of synthetic aviation fuels as outlined in ASTM D4054, and the more accurate group-type analysis results provided by GCxGC assist with streamlining the acceptance process.

Ginger Oil Analysis and Grade Differentiation with Pegasus BTX Using Hydrogen Carrier Gas

Pegasus BTX and ChromaTOF Sync Application Note - Thyme Varieties

Joining us from the University of Messina, Mariosimone Zoccali, Assistant Professor of Analytical Chemistry, present on 'Boosting Food Analysis Using GCxGC-ToFMS. In his talk, Prof. Zoccali explores the pioneering applications of Comprehensive Two-Dimensional Gas Chromatography coupled with Time-of-Flight Mass Spectrometry in the analysis of extra virgin olive oil (EVOO), measured on our newly released Pegasus BTX GCxGC-ToF MS. He shows how this advanced technique provides insights in both targeted and non-targeted analyses , offering deeper understanding into EVOO's chemical profiles. Dr. Zoccali highlights how GCxGC-ToF MS enhances the detection of contaminants and key compounds, such as antioxidants and sterols, which are essential for assessing quality, authenticity and flavor.

Part of the 2024 Non-Target Screen Webinar Series

Joining us from University of Southampton, Prof. John Langley, Head of Characterisation and Analytics, Chemistry, present on the latest advancements in renewable and sustainable fuel analysis. Prof. Langley explores how these next-generation fuels introduce new hurdles for quality measurement, requiring innovative hyphenated techniques, including GC-MS and comprehensive two-dimensional gas chromatography (GCxGC-MS). He discusses how GCxGC-MS is pivotal for comparing and analyzing different HVOs, providing clarity on how these tools enable the screening of differences and similarities across various renewable fuel sources.

Part of the 2024 Non-Target Screen Webinar Series

Joining us from William and Mary, Dr. Katelynn A. Perrault Uptmor, PI of the Nontargeted Separations Laboratory , present her work of screening samples using comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry (GCXGC-TOFMS) in forensic applications as novel types of evidence appear. Dr. Perrault Uptmor highlights initial approaches to method development for new samples and show recent applications related to chemical profiling of deposited fingermarks, organic gunshot residue and decomposition odor. She also discusses the implications of GCXGC-TOFMS sample visualization in the context of expert testimony for communicating screening processes in forensic casework within the courtroom.

Part of the 2024 Non-Target Screen Webinar Series