LECO Solutions for Pharma

In the high-stakes world of pharmaceutical research and development, where precision, reliability, and regulatory compliance are paramount, LECO’s advanced analytical instruments provide the cutting-edge technology needed to accelerate drug discovery and ensure product safety. Our state-of-the-art solutions offer pharmaceutical researchers and quality control teams several compelling advantages:

1. Accelerated Drug Discovery: LECO’s high-resolution time-of-flight mass spectrometry (HRTOF-MS) technology enables rapid identification and characterization of novel compounds, metabolites, and impurities, streamlining the drug discovery process.
2. Comprehensive Extractables and Leachables Analysis: Our advanced GC-MS and LC-MS systems provide unparalleled sensitivity and selectivity for detecting and identifying potential leachables from packaging materials, ensuring drug product safety and stability.
3. Enhanced Metabolite Profiling: LECO’s innovative metabolomics platforms offer deep insights into drug metabolism and pharmacokinetics, facilitating more informed decision-making in lead optimization and candidate selection.
4. Trace-Level Contaminant Detection: With industry-leading sensitivity, our instruments excel at identifying trace-level impurities and degradation products, critical for meeting stringent regulatory requirements.
5. Versatile Application Range: From early-stage drug discovery to formulation development and quality control, LECO’s diverse instrument portfolio adapts to various pharmaceutical workflows.
6. Data Integrity and Compliance: Our software solutions are designed with regulatory compliance in mind, featuring robust data security, audit trails, and electronic signatures to meet GMP and 21 CFR Part 11 requirements.
7. High-Throughput Capabilities: Rapid analysis times and automated sample handling increase productivity in both R&D and QC environments, accelerating time-to-market for new drugs.
8. Expert Pharmaceutical Support: LECO’s dedicated team of pharmaceutical specialists provides ongoing application support and training, ensuring you stay at the forefront of analytical techniques in drug discovery and package leaching studies.

By choosing LECO for your pharmaceutical research and quality control needs, you’re not just acquiring an instrument – you’re gaining a partner committed to accelerating your drug discovery process, ensuring product safety, and navigating the complex landscape of pharmaceutical analytics and regulatory compliance.

Application Notes

Learn more with our latest Pharma application notes.

• A Comprehensive GC-TOFMS Metabolomics Workflow

  Early Type 2 Diabetes prediction can be facilitated by the implementation of a metabolomics method for the identification of T2DM biomarkers. A complete automated derivatization workflow is explored.

• Using High Performance GC-TOFMS to Effectively Monitor Patients for Opioids and other Drug Classes

• Deadly Counterfeit Pills: Untargeted Analysis of Fentanyl-Laced Drugs

• Cannabis Analysis: Hemp Potency Determination

• Determination of Moisture in Cannabis

Videos

Watch our most recent videos on Pharma.

• Science from Beyond the Grave: a Virtual GC Symposium

  Three GC/MS Experts embrace the 'spookier' side of mass spectrometry.
  
  Jane Hill, from the University of British Columbia, brings her expertise on 'omics and medical diagnostics in Disease: Trick or Treat? Metabolomics is changing how we monitor our health
  
  Albert Lebedev, professor at the Faculty of Chemistry at Moscow State University, has suggestions and advice for what to do if you meet a mummy (and happen to have access to mass spectrometry!) in What Mass Spectrometry can tell you about 5000 year old Mummies
  
  Shari Forbes, Director of Canada's Secure Site for Research in Thanatology, will finish the symposium with a look into GCxGC mass spectrometry and the wider range of research and training that can come from Canada's first body farm in Death, Decomposition and Dogs

• Multiclass GCxGC Method for Cannabis Products

  Lorne Fell [LECO] provides an update on LECO Separation Science instruments and equipment. Jean-François Focant [University of Liège] presents "Multiclass GCxGC Method for Cannabis Products", discussing how GCxGC can be utilized to study cannabis strains for CBD content.

• Characterization of Beverage Products Containing Cannabidiol

  Liz Humston-Fulmer [LECO] utilized GCxGC TOF-MS technologies to understand the chemical composition of CBD-infused beverages. Originally presented 26 March 2020.