GCxGC Video

Joining us from the University of Messina, Mariosimone Zoccali, Assistant Professor of Analytical Chemistry, present on 'Boosting Food Analysis Using GCxGC-ToFMS. In his talk, Prof. Zoccali explores the pioneering applications of Comprehensive Two-Dimensional Gas Chromatography coupled with Time-of-Flight Mass Spectrometry in the analysis of extra virgin olive oil (EVOO), measured on our newly released Pegasus BTX GCxGC-ToF MS. He shows how this advanced technique provides insights in both targeted and non-targeted analyses , offering deeper understanding into EVOO's chemical profiles. Dr. Zoccali highlights how GCxGC-ToF MS enhances the detection of contaminants and key compounds, such as antioxidants and sterols, which are essential for assessing quality, authenticity and flavor.

Part of the 2024 Non-Target Screen Webinar Series

Joining us from William and Mary, Dr. Katelynn A. Perrault Uptmor, PI of the Nontargeted Separations Laboratory , present her work of screening samples using comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry (GCXGC-TOFMS) in forensic applications as novel types of evidence appear. Dr. Perrault Uptmor highlights initial approaches to method development for new samples and show recent applications related to chemical profiling of deposited fingermarks, organic gunshot residue and decomposition odor. She also discusses the implications of GCXGC-TOFMS sample visualization in the context of expert testimony for communicating screening processes in forensic casework within the courtroom.

Part of the 2024 Non-Target Screen Webinar Series

Joining us from The Open University, UK, Dr. Geraint Huw Morgan, STEM Research Infrastructure Lead and Director of the Centre for Analytical Solutions, present an in-depth exploration of non-targeted screening techniques for complex aroma profiles. Drawing on his extensive experience in developing advanced methods for volatile organic compounds (VOCs), Dr. Morgan highlights innovative approaches and methodologies using advanced technologies like GCxGC-MS, and TOF-MS.

Part of the 2024 Non-Target Screen Webinar Series

Joining us from University of Liège in Belgium, Jef Focant and PH Stefanuto present how the Organic Biological Analytical Chemistry Group utilizes GCxGC-TOFMS in their research. Focant provides a comprehensive overview of testing complex matrices samples, demonstrating the wealth of information that can be gained from analyses across various metabolomics applications. Stefanuto explores the microbiome, offering insight into the using GCxGC-TOFMS to unravel complex samples, paving the way for innovative discoveries.

Part of the 2024 Non-Target Screen Webinar Series

Professor Susan Richardson from the University of South Carolina will delve into her groundbreaking research on a newly discovered class of disinfection byproducts in drinking water. Using advanced techniques such as gas chromatography coupled with high-resolution mass spectrometry, Professor Richardson sheds light on the implications for water safety and public health. Discover the benefits of mass spectrometry for environmental analysis and gain insight into the future of drinking water quality assessment.

Part of the 2024 Non-Target Screen Webinar Series

We explore the capabilities of LECO technology and the impact it is having on overcoming the challenges faced in the Aroma, Flavor, and Fragrance industry.

Dr. Heather Bean (Arizona State University) discusses using GCxGC-TOF MS to detect and phenotype infections directly from lung samples.

When you don't know what you're looking for, as is often the case with environmental contaminants and pollutants, the task can seem daunting, but high-resolution TOFMS and GCxGC is a powerful combination for non-target searches. With the tools included with the Pegasus® HRT4D and the Multi-Mode Source™ (MMS™), identification of unknowns can be vastly improved and assigned higher confidence.

Small time savings throughout the workflow can add up to big savings. See aroma and flavor examples of how automated sample prep and elevated Time-of-Flight Mass Spectrometry (TOFMS) analysis, followed by software solutions to compare and evaluate data and results, can save your lab time and resources.

Helium is becoming an increasingly limited natural resource; using Hydrogen to achieve increased chromatographic throughput in GC applications is attractive. Both have advantages and disadvantages. LECO experts investigated the use of Hydrogen as a carrier gas for GC-TOF-MS analysis. Nick Jones, LECOs Global Application and Development Director (Separation Sciences) presents the method transfer approaches used, the technological benefits, and application examples in the presentation below.

With ever-increasing demands on your time, labor, and resources, optimizing your workflow is essential. Learn best approaches from GC-TOFMS experts to enhance your one- and two-dimensional gas chromatography applications (GC-MS and GCxGC-MS) in this webinar.

How do we find what we don't specifically look for? This presentation will look at non-target GCxGC for environmental forensics, or exposomic analysis, of wastewater, specifically the semivolatile organic fraction, and what can be done when discovered non-targets may present health impacts. Frank L. Dorman, Penn State University Dept of Biochemistry and Molecular Biology & Dartmouth College Dept of Chemistry

Christina Kelly (LECO Applications Chemist) demonstrates how to use the classification tools of ChromaTOF® software. Presented as a portion of the LECO 2020 GCxGC Symposium.

Copresenters Renee Cataneo & Mayur Mundada [Menssana Research Inc.] discuss data obtained through GCxGC TOF-MS analysis of breath samples. Originally presented 20 September 2012.

Three GC/MS Experts embrace the 'spookier' side of mass spectrometry.

Jane Hill, from the University of British Columbia, brings her expertise on 'omics and medical diagnostics in Disease: Trick or Treat? Metabolomics is changing how we monitor our health

Albert Lebedev, professor at the Faculty of Chemistry at Moscow State University, has suggestions and advice for what to do if you meet a mummy (and happen to have access to mass spectrometry!) in What Mass Spectrometry can tell you about 5000 year old Mummies

Shari Forbes, Director of Canada's Secure Site for Research in Thanatology, will finish the symposium with a look into GCxGC mass spectrometry and the wider range of research and training that can come from Canada's first body farm in Death, Decomposition and Dogs

The Czech Agriculture and Food Inspection Authority has been using GCxGC-TOFMS for the analysis of pesticide residues in food of plant origin since 2005. Radim Stepan will talk about the advances in the instruments and the analyses they have used for pesticide residue analysis in cooperation with the University of Chemistry and Technology Prague.

The current analytical method for the quantitative determination of Mineral Oil Saturated Hydrocarbons (MOSH) and Mineral Oil Aromatic Hydrocarbons (MOAH) is LC-GC-FID, but the chromaticagraphic profile obtained is too often just a hump of unresolved substances. However, GCxGC-TOFMS/FID is the most promising solution to characterize MOSH and MOAH in detail and to detect markers that can help identify and act on the source of contamination. Giorgia Purcaro [University of Liege] will introduce the challenges of MOSH/MOAH analysis and talk about what adding a GCxGC-TOFMS analysis to your process can do for your results.

Lorne Fell [LECO] provides an update on LECO Separation Science instruments and equipment. Jean-François Focant [University of Liège] presents "Multiclass GCxGC Method for Cannabis Products", discussing how GCxGC can be utilized to study cannabis strains for CBD content.

Rob Synovec [University of Washington] discusses discovery-based analysis and its application into gas chromatography, and the development of ChromaTOF® Tile, a tile-based fisher ratio analysis tool. [Synovec presentation begins at 14:00]

Liz Humston-Fulmer [LECO] utilized GCxGC TOF-MS technologies to understand the chemical composition of CBD-infused beverages. Originally presented 26 March 2020.