Mass Spectrometry Application Notes

Comprehensive two-dimensional gas chromatography with flame ionization detection (GCxGC-FID) has proven to be one of the most effective analytical methods for analyzing complex mixtures, allowing for the detailed separation and identification of the hydrocarbons present while providing efficient, high-resolution chromatographic separations.

This application note describes how to use a simple workflow with the LECO Paradigm system to fulfill the requirements of the ASTM D8396 test method to quantitatively determine mass % of total n-paraffins, iso-paraffins, naphthenes, 1-ring aromatics, and 2-ring aromatics using reverse-fill flush flow modulated comprehensive two-dimensional gas chromatography–flame ionization detection (GCxGC-FID). Understanding of bulk composition is crucial for fast-track certification of synthetic aviation fuels as outlined in ASTM D4054, and the more accurate group-type analysis results provided by GCxGC assist with streamlining the acceptance process.

Ginger Oil Analysis and Grade Differentiation with Pegasus BTX Using Hydrogen Carrier Gas

Pegasus BTX and ChromaTOF Sync Application Note - Thyme Varieties

Pegasus BTX 4D Application Note - Synthetic Aviation Fuels

Pegasus BTX Application Note - PFAS

Pegasus BTX Application Snapshot - Molassess

Pegasus BTX 4D Application Snapshot - HTL Pyrolysis Gasoline

Wildfires increase the risk of negative chemical reactions with municipal water treatment processes.

Pegasus BTX 4D Application Snapshot - Basil

In this Application Note, we use comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry (GCxGC-TOFMS) and ChromaTOF Tile, a statistical analysis software for GCxGC data, to differentiate perfume samples.

The production of coffee and process development of new coffee variants and substitutes (caffeine free, alternative taste, and aroma profiles, etc.), is a huge industry globally. The ability to guarantee the safety of these products while also monitoring the flavour and aroma qualities of products to meet consumer expectations and preferences is vital. Here, a method for simultaneous analysis of Furans and Non-Target Screening (NTS) of other key compounds, such as aroma-active species, is demonstrated.

Data from a single injection of plastics-derived pyrolysis oil using GCxGC with reverse fill-flush modulator and flow splitter is explored.

Chromatograms of perfume sample obtained with use of reverse fill-flush modulator and flow splitter are analyzed

Flow modulation provides high accuracy group-type analyses for traditional fuels and emerging alternatives.

Data demonstrating how Paradigm reverse-fill flush modulator and Shift flow splitter enhance GCxGC detection accuracy in fragrance samples.

Aroma Compounds Pumpernickel Bread

Heavy Fuel Oil Multi-Mode Source MMS GCxGC-HRT4D

Early Type 2 Diabetes prediction can be facilitated by the implementation of a metabolomics method for the identification of T2DM biomarkers. A complete automated derivatization workflow is explored.